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Understanding how to use DMSO Dimethyl Sulfoxide properly is crucial for maximising its potential benefits and minimising risks. Typically available in liquid or gel forms, DMSO is generally applied topically to the affected area. Start with a patch test to ensure no adverse skin reactions occur. After receiving approval from your healthcare provider, apply a small amount of DMSO to clean, dry skin using a cotton ball or pad. Always wear gloves to avoid skin irritation. Never mix DMSO with other substances unless advised by a medical professional.